<scp>DPP</scp>‐4 Inhibitor Linagliptin Attenuates A<i>β</i>‐induced Cytotoxicity through Activation of <scp>AMPK</scp> in Neuronal Cells

Abstract

Taken together, our findings suggest linagliptin can restore the impaired insulin signaling caused by Aβ in neuronal cells, suggesting DPP-4 inhibitors may have therapeutic potential for reducing Aβ-induced impairment of insulin signaling and neurotoxicity in AD pathogenesis.