Rescue of chloride and bicarbonate transport by elexacaftor-ivacaftor-tezacaftor in organoid-derived CF intestinal and cholangiocyte monolayers - Concepedia

Concepedia

Publication | Open Access

Rescue of chloride and bicarbonate transport by elexacaftor-ivacaftor-tezacaftor in organoid-derived CF intestinal and cholangiocyte monolayers

DOI Full Paper Access

26

Citations

20

References

2021

Year

Marcel J. C. Bijvelds, Floris J.M. Roos, Kelly F. Meijsen, Henk P. Roest, Monique M.A. Verstegen, Hettie M. Janssens, Luc J. W. van der Laan, Hugo R. de Jonge

Journal of Cystic Fibrosis

Abstract

ELX/IVA/TEZ has the potential to restore both chloride and bicarbonate secretion across CF intestinal and biliary epithelia and may counter luminal hyper-acidification in these tissues.

References

	Year	Citations

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