Bone marrow-derived mesenchymal stem cells inhibits hepatocyte apoptosis after acute liver injury.

Yijing Cai, Zhuolin Zou, Liyuan Liu, Si Chen, Yi Chen, Zhuo Lin, Keqing Shi, Lanman Xu, Yongping Chen

PubMed · 2015 · 34 citations · 20 references

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Abstract

BMSCs transplantation could significantly restore liver function. These effects were supposed to be mediated by suppressing hepatocyte apoptosis as well as promoting proliferation. Reduction of apoptosis seemed to correlate with mitochondria-dependent-pathway.

References

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