Piperlongumine is a novel nuclear export inhibitor with potent anticancer activity

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Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

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CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications

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Antifungal amides from Piper hispidum and Piper tuberculatum

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Life Sciences, Biology, Medicinal Chemistry +9

Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs

Drew Adams, Mingji Dai, Giovanni Pellegrino et al. · Proceedings of the National Academy of Sciences · 2012 · 224 citations · Full text

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