Prostaglandin E2, prostacyclin, and thromboxane changes during nonpulsatile cardiopulmonary bypass in humans

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Complement Activation during Cardiopulmonary Bypass

Dennis E. Chenoweth, Steven W. Cooper, Tony E. Hugli et al. · New England Journal of Medicine · 1981 · 1.2K citations

Medicine, Immunology, Surgery +12

NEW CYTOPLASMIC COMPONENTS IN ARTERIAL ENDOTHELIA

Ewald R. Weibel, George E. Palade · The Journal of Cell Biology · 1964 · 1.1K citations · Full text

Medicine, Anatomy, Cell Biology +13

Hemodialysis leukopenia. Pulmonary vascular leukostasis resulting from complement activation by dialyzer cellophane membranes.

P R Craddock, Jan Fehr, A P Dalmasso et al. · Journal of Clinical Investigation · 1977 · 1K citations · Full text

Medicine, Hematology, Immunology +17

Prostaglandins: Their Disappearance from and Release into the Circulation

S. H. Ferreira, John R. Vane · Nature · 1967 · 899 citations

Life Sciences, Biochemistry, Pharmacology +5