Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3

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Primary Immunodeficiency, Immunogenetics, Immune Deficiency +10

Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development

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Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

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Immunology, Cell Death, Immunotherapy +21