Concepedia

Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity

Hannah L. Peters, Dirk Jochmans, Adriaan H. de Wilde, Clara C. Posthuma, Eric J. Snijder, Johan Neyts, Katherine L. Seley‐Radtke

Bioorganic & Medicinal Chemistry Letters · 2015 · 88 citations · 22 references

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Coronavirus as a possible cause of severe acute respiratory syndrome

ST Lai, Yi Guan, Lyc Yam et al. · The Lancet · 2003 · 3K citations · Full text

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Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

Adriaan H. de Wilde, Dirk Jochmans, Clara C. Posthuma et al. · Antimicrobial Agents and Chemotherapy · 2014 · 750 citations · Full text

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In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds

Feng Chen, Kwok Hung Chan, Yong Jiang et al. · Journal of Clinical Virology · 2004 · 541 citations · Full text

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Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics

Everett Clinton Smith, Hervé Blanc, Marco Vignuzzi et al. · PLoS Pathogens · 2013 · 487 citations · Full text

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Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV–infected rhesus macaques

Darryl Falzarano, Emmie de Wit, Angela L. Rasmussen et al. · Nature Medicine · 2013 · 452 citations · Full text

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