Adriaan H. de Wilde

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

Adriaan H. de Wilde, Dirk Jochmans, Clara C. Posthuma et al. · Antimicrobial Agents and Chemotherapy · 2014 · 746 citations · Full text

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

Eric J. Snijder, Ronald W.A.L. Limpens, Adriaan H. de Wilde et al. · PLoS Biology · 2020 · 466 citations · Full text

Viral Replication, Immunology, Viral Pathogenesis +17

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

Rinke Bos, Lucy Rutten, Joan E. M. van der Lubbe et al. · npj Vaccines · 2020 · 367 citations · Full text

Immunology, Immunodominance, Immunotherapeutics +18

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

Adriaan H. de Wilde, V. Stalin Raj, Diede Oudshoorn et al. · Journal of General Virology · 2013 · 358 citations · Full text

Viral Replication, Microbial Pathogens, Viral Pathogenesis +17

Cyclosporin A inhibits the replication of diverse coronaviruses

Adriaan H. de Wilde, Jessika C. Zevenhoven-Dobbe, Yvonne van der Meer et al. · Journal of General Virology · 2011 · 246 citations · Full text

Csa Treatment, Viral Replication, Viral Persistence +13