Ronald W.A.L. Limpens

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

Natacha S. Ogando, Tim J. Dalebout, Jessika C. Zevenhoven-Dobbe et al. · Journal of General Virology · 2020 · 627 citations · Full text

Sudden Emergence, Sars Viruses, Viral Replication +14

A molecular pore spans the double membrane of the coronavirus replication organelle

Georg Wolff, Ronald W.A.L. Limpens, Jessika C. Zevenhoven-Dobbe et al. · Science · 2020 · 533 citations · Full text

Viral Replication, Synthetic Virology, Molecular Biology +17

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

Eric J. Snijder, Ronald W.A.L. Limpens, Adriaan H. de Wilde et al. · PLoS Biology · 2020 · 466 citations · Full text

Viral Replication, Immunology, Viral Pathogenesis +17

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

Adriaan H. de Wilde, V. Stalin Raj, Diede Oudshoorn et al. · Journal of General Virology · 2013 · 358 citations · Full text

Viral Replication, Microbial Pathogens, Viral Pathogenesis +17

Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication

Diede Oudshoorn, Kevin Rijs, Ronald W.A.L. Limpens et al. · mBio · 2017 · 247 citations · Full text