Update of the drug resistance mutations in HIV-1: March 2013.

Abstract

<i>OATP1B3</i> operates as an in vivo PAI reporter gene based on its ability to promote the cellular uptake of ICG. Benefits include the human derivation of <i>OATP1B3</i>, combined with the use of wavelengths in the near-infrared region, high extinction coefficient, low quantum yield, and clinical approval of ICG. The authors posit that this system will be useful for localized monitoring of emerging gene- and cell-based therapies in clinical applications.© RSNA, 2019<b>Keywords:</b> Animal Studies, Molecular Imaging, Molecular Imaging-Clinical Translation, Molecular Imaging-Reporter Gene Imaging, Optical Imaging<i>Supplemental material is available for this article.</i>