Concepedia

Publication | Closed Access

Sphingosine‐1‐phosphate promotes tumor development and liver fibrosis in mouse model of congestive hepatopathy

DOI

70

Citations

28

References

2021

Year

Hironari Kawai, Yosuke Osawa, Michitaka Matsuda, Tomoyuki Tsunoda, K. Yanagida, Daisuke Hishikawa, Miku Okawara, Yuzuru Sakamoto, Tomonari Shimagaki, Yuriko Tsutsui,
Hepatology

Abstract

In conclusion, chronic liver congestion promotes HCC development and liver fibrosis by S1P production from LPS-induced capillarized LSECs. Careful treatment of both RHF and liver cancer might be necessary for patients with RHF with primary or metastatic liver cancer.

References

YearCitations

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