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Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

Jie Liang, Masayuki Nagahashi, Eugene Y. Kim, Kuzhuvelil B. Harikumar, Akimitsu Yamada, Wei‐Ching Huang, Nitai C. Hait, Jeremy C. Allegood, Megan M. Price, Dorit Avni,

Cancer Cell · 2012 · 558 citations · 52 references

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52

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Florian R. Greten, Lars Eckmann, Tim F. Greten et al. · Cell · 2004 · 2.4K citations · Full text

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Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

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IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei I. Grivennikov, Eliad Karin, Janoš Terzić et al. · Cancer Cell · 2009 · 2.1K citations · Full text

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

Shaoguang Wu, Ki‐Jong Rhee, Emilia Albesiano et al. · Nature Medicine · 2009 · 1.8K citations · Full text

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Enhanced Th1 Activity and Development of Chronic Enterocolitis in Mice Devoid of Stat3 in Macrophages and Neutrophils

Kiyoshi Takeda, Björn E. Clausen, Tsuneyasu Kaisho et al. · Immunity · 1999 · 1.2K citations · Full text

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