Automated QuEChERS for the determination of 482 pesticide residues in Radix codonopsis by GC-Q-TOF/MS and LC-Q-TOF/MS

Abstract

424. Besides, the automated workstation presented lower RSD (more pesticides ≤10%) and better recovery quality (more pesticides within 90-110%). Following the method verification, 50 Radix codonopsis samples purchased from local markets were prepared with the automated workstation and analyzed by GC and LC-Q-TOF/MS. 18 pesticides were detected in 38 samples, one of which was a highly toxic pesticide. The automated QuEChERS workstation can handle 40 samples in one cycle within 6 hours, and realize whole-process automation covering from samples after "weighing" to "injection into vials". The batch-to-batch, day-to-day, and lab-to-lab consistency and 24 × 7 workability of the automated solution have demonstrated a promising and ideal replacement for manual operation in sample preparation.