Concepedia

Exploring the Protective and Reparative Mechanisms of G. lucidum Polysaccharides Against H2O2-Induced Oxidative Stress in Human Skin Fibroblasts

Xiuqin Shi, Wenjing Cheng, Qian Wang, Jiachan Zhang, Changtao Wang, Meng Li, Dan Zhao, Dongdong Wang, Quan An

Clinical Cosmetic and Investigational Dermatology · 2021 · 32 citations · 38 references

DOIFull text

Open access

Abstract

The results showed that GLP could protect human skin fibroblasts from oxidative damage caused by H<sub>2</sub>O<sub>2</sub> peroxide by enhancing enzyme activity and activating Keap1-Nrf2/ARE signaling pathway. GLP will act as a natural antioxidant to protect the skin from oxidative stress damage.

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