Precise genomic deletions using paired prime editing

Multiplex Genome Engineering Using CRISPR/Cas Systems

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Life Sciences, Genetics, Molecular Genetics +16

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Dan Dominissini, Sharon Moshitch-Moshkovitz, Schraga Schwartz et al. · Nature · 2012 · 5K citations

Life Sciences, Bioinformatics, Genetics +11

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 5K citations

Life Sciences, Biotechnology, Molecular Biology +13

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

Jiajie Zhang, Kassian Kobert, Tomáš Flouri et al. · Bioinformatics · 2013 · 4.9K citations · Full text

Life Sciences, Bioinformatics, Genomic Data Analysis +15