Novel Symbiotic Genome-Scale Model Reveals <i>Wolbachia</i> 's Arboviral Pathogen Blocking Mechanism in Aedes aegypti

Abstract

Arboviral diseases such as Zika and Dengue have been on the rise mainly due to climate change, and the development of new treatments and strategies to limit their spreading is needed. The use of Wolbachia as an approach for disease control has motivated new research related to the characterization of the mechanisms that underlie its pathogen-blocking properties.