Concepedia

Retinoic acid rewires the adrenergic core regulatory circuitry of childhood neuroblastoma

Mark W. Zimmerman, Adam D. Durbin, Shuning He, Felix Oppel, Hui Shi, Ting Tao, Zhaodong Li, Alla Berezovskaya, Yu Liu, Jinghui Zhang,

Science Advances · 2021 · 65 citations · 38 references

DOIFull text

Open access

Concepts

Abstract

Retinoic acid reprograms neuroblastoma cell identity by remodeling the core transcriptional regulatory circuitry.

References

38

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.3K citations · Full text

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Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz, Brian J. Abraham, Tong Ihn Lee et al. · Cell · 2013 · 3.9K citations · Full text

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Identification of a receptor for the morphogen retinoic acid

Vincent Giguère, Estelita S. Ong, Prudimar Segui et al. · Nature · 1987 · 2K citations

, , +12

Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13-<i>cis</i>-Retinoic Acid

Katherine K. Matthay, Judith G. Villablanca, Robert C. Seeger et al. · New England Journal of Medicine · 1999 · 1.9K citations · Full text

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Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-<i>cis</i>-Retinoic Acid: A Children's Oncology Group Study

Katherine K. Matthay, C. Patrick Reynolds, Robert C. Seeger et al. · Journal of Clinical Oncology · 2009 · 856 citations

, , +6