Basic Research in Cardiology · 2021 · 53 citations · 30 references
Life SciencesCardiologyCell BiologyApoptosisAutophagyMitochondrial BiologyMitochondrial PhysiologyMitochondrial TransportMitophagyMyocardial ProtectionZinc MetabolismMitochondrial Membrane TransportersMitophagy SignalingMitophagy TransportMyocardial Ischemia-reperfusion InjuryZinc Transport Proteins
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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.7K citations
Ubiquitin is phosphorylated by PINK1 to activate parkin
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CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis
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