Concepedia

Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers

Eva M. López‐Vidal, Carly K. Schissel, Somesh Mohapatra, Kamela Bellovoda, Chia-Ling Wu, Jenna Wood, Annika B. Malmberg, Andrei Loas, Rafael Gómez‐Bombarelli, Bradley L. Pentelute

JACS Au · 2021 · 24 citations · 28 references

DOIFull text

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Concepts

Abstract

was able to deliver an enzyme to the cytosol of cells. Our findings suggest that, given a data set of long CPPs, we can discover by extrapolation short, active sequences that deliver antisense oligomers.

References

28

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Text Data Augmentation for Deep Learning

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The crystal structure of diphtheria toxin

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Search for inhibitors of endocytosis

Dipannita Dutta, Julie G. Donaldson · Cellular Logistics · 2012 · 435 citations · Full text

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