Concepedia

Sequence-function Relationships

Sequence–Function Relationships is a theoretical construct that characterizes the mapping between the primary structure of biomolecules and their biochemical activities by specifying how variations in sequence determine functional outcomes within the context of directed evolution and molecular fitness landscapes.

371

Publications

33.5K

Citations

1.6K

Authors

538

Institutions

Publications per year

2017–2026

123

Parents

Publications

371

CDD: a Conserved Domain Database for the functional annotation of proteins

Aron Marchler‐Bauer, Shuo Lu, J. B. Anderson et al. · Nucleic Acids Research · 2010 · 3.2K citations · Full text

, , +15

PANTHER: A Library of Protein Families and Subfamilies Indexed by Function

Paul D. Thomas, Michael J. Campbell, Anish Kejariwal et al. · Genome Research · 2003 · 3.1K citations · Full text

, , +15

The human olfactory receptor gene family

Bettina Malnic, Paul A. Godfrey, Linda B. Buck · Proceedings of the National Academy of Sciences · 2004 · 618 citations · Full text

, , +17

High-resolution mapping of protein sequence-function relationships

Douglas M. Fowler, Carlos L. Araya, Sarel J. Fleishman et al. · Nature Methods · 2010 · 612 citations · Full text

, , +14

Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools

Paul D. Thomas, Anish Kejariwal, Nan Guo et al. · Nucleic Acids Research · 2006 · 517 citations · Full text

, , +15

1–5 of 371

Authors

1.6K

  1. JM
    Janusz M. Bujnicki

    International Institute of Molecular and Cell Biology, Poland

    10 publications · 564 citations

    10

    h-index

  2. PA
    Philip A. Romero

    University of Wisconsin–Madison, United States

    8 publications · 598 citations

    8

    h-index

  3. JP
    Jürgen Pleiss

    University of Stuttgart, Germany

    6 publications · 261 citations

    6

    h-index

  4. PC
    Patricia C. Babbitt

    University of California, San Francisco, United States

    5 publications · 490 citations

    5

    h-index

  5. LS
    Liskin Swint‐Kruse

    University of Kansas Medical Center, United States

    5 publications · 140 citations

    5

    h-index

1–5 of 1.6K

Institutions

538

  1. Harvard University

    Cambridge, United States

    13 h-index

    38 publications

    1.5K citations

  2. University of Wisconsin–Madison

    Madison, United States

    12 h-index

    57 publications

    3.7K citations

  3. Center for Systems Biology

    Boston, United States

    11 h-index

    27 publications

    1K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    33 publications

    8.8K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    40 publications

    4.3K citations

  6. International Institute of Molecular and Cell Biology

    Warsaw, Poland

    10 h-index

    30 publications

    2K citations

  7. University of California San Diego

    San Diego, United States

    8 h-index

    25 publications

    2.9K citations

  8. Chinese Academy of Sciences

    Beijing, China

    8 h-index

    38 publications

    1.4K citations

1–8 of 538

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 3K citations

    17

    h-index

  2. Nucleic Acids Research

    18 publications · 4.9K citations

    16

    h-index

  3. Nature Communications

    14 publications · 920 citations

    14

    h-index

  4. PLoS ONE

    14 publications · 476 citations

    14

    h-index

  5. BMC Bioinformatics

    15 publications · 647 citations

    13

    h-index

1–5