Concepedia

Integrated single-cell transcriptomics and epigenomics reveals strong germinal center–associated etiology of autoimmune risk loci

Hamish W. King, Kristen L. Wells, Zohar Shipony, Arwa S. Kathiria, Lisa E. Wagar, Caleb A. Lareau, Nara Orban, Robson Capasso, Mark M. Davis, Lars M. Steinmetz,

Science Immunology · 2021 · 57 citations · 64 references

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Abstract

). Together, these analyses provide a powerful new cell type–resolved resource for the interpretation of cellular and genetic causes underpinning autoimmune disease.

References

64

Model-based Analysis of ChIP-Seq (MACS)

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Comprehensive Integration of Single-Cell Data

Tim Stuart, Andrew Butler, Paul Hoffman et al. · Cell · 2019 · 16.9K citations · Full text

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

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Fast, sensitive and accurate integration of single-cell data with Harmony

Ilya Korsunsky, Nghia Millard, Jean Fan et al. · Nature Methods · 2019 · 10.5K citations · Full text

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Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Jason D. Buenrostro, Paul G. Giresi, Lisa C. Zaba et al. · Nature Methods · 2013 · 7K citations · Full text

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