Concepedia

Parkin Prevents Glutamate Excitotoxicity Through Inhibiting NLRP3 Inflammasome in Retinal Ganglion Cells

Xiuquan Wu, Yanan Dou, Zhou Fei, Fei Fei

Neuroscience · 2021 · 17 citations · 30 references

DOI

Concepts

References

30

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 4K citations · Full text

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.7K citations

, , +13

RETRACTED ARTICLE: Parkin and PINK1 mitigate STING-induced inflammation

Danielle A. Sliter, Jennifer Martinez, Ling Hao et al. · Nature · 2018 · 1.3K citations · Full text

, , +11

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

Yun Chen, Gerald W. Dorn · Science · 2013 · 1.3K citations

, , +16

Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

Hua Jiang, Hongbin He, Yun Chen et al. · The Journal of Experimental Medicine · 2017 · 729 citations · Full text

, , +15