Dual-targeting CAR-T cells with optimal co-stimulation and metabolic fitness enhance antitumor activity and prevent escape in solid tumors

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CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

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Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

Alice L. Yu, Andrew L. Gilman, M. Fevzi Özkaynak et al. · New England Journal of Medicine · 2010 · 1.8K citations · Full text

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A distinct “side population” of cells with high drug efflux capacity in human tumor cells

Charlotte Hirschmann-Jax, Angela E. Foster, Gerald Wulf et al. · Proceedings of the National Academy of Sciences · 2004 · 1.3K citations

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Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Omkar U. Kawalekar, Roddy S. O’Connor, Joseph A. Fraietta et al. · Immunity · 2016 · 1.2K citations · Full text

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