Astrocytic Kir4.1 regulates NMDAR/calpain signaling axis in lipopolysaccharide-induced depression-like behaviors in mice

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

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Life Sciences, Immunology, Medicinal Chemistry +15

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

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Life Sciences, Immunology, Microbiology +16

Changes in the global burden of depression from 1990 to 2017: Findings from the Global Burden of Disease study

Qingqing Liu, Hairong He, Yang Jin et al. · Journal of Psychiatric Research · 2019 · 1.5K citations · Full text

Public Health, Population Health Sciences, Psychiatry +17

Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

Yan Yang, Yihui Cui, Kangning Sang et al. · Nature · 2018 · 1.1K citations

Medicine, Neurobiology, Neuroscience +10

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

William A. Banks, Alicia M. Gray, Michelle A. Erickson et al. · Journal of Neuroinflammation · 2015 · 625 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17