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Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making

Medicinal ChemistrySupport Regulatory Decision-makingPharmacokinetic ModelingPharmacodynamicsBiochemistryMedicineNatural SciencesBioanalysisEntrectinib ParentPhysiologically-based Pharmacokinetic ModellingPharmacological StudyPharmacotherapyMetabolomicsSystems BiologyPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsDrug Discovery