Concepedia

Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

Fansen Meng, Zhengyang Yu, Dan Zhang, Shasha Chen, Hongxin Guan, Ruyuan Zhou, Qirou Wu, Qian Zhang, Shengduo Liu, Mukesh Kumar Venkat Ramani,

Molecular Cell · 2021 · 128 citations · 58 references

DOI

Concepts

References

58

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao, Xiaomu Wei, Weiquan Li et al. · Genes & Development · 2007 · 3.2K citations · Full text

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IKKε and TBK1 are essential components of the IRF3 signaling pathway

Katherine A. Fitzgerald, Sarah M. McWhirter, Daniel C. Rowe et al. · Nature Immunology · 2003 · 2.7K citations

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