Ferromagnetic soft continuum robots

Yoonho Kim, German Alberto Parada, Shengduo Liu, +1

Science Robotics

HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity

Shiying Wu, Qian Zhang, Fei Zhang, +14

Nature Cell Biology

Sting SignallingViral ImmunityImmunologyAntitumour ImmunityImmunologic Mechanism +6

A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis

Dan Zhang, Yutong Liu, Yezhang Zhu, +13

Nature Cell Biology

InflammationFibrosisSignal TransductionOrgan FibrosisSignaling Pathway +9

Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade

Qian Zhang, Fansen Meng, Shasha Chen, +13

Nature Cell Biology

Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity

Fansen Meng, Zhengyang Yu, Dan Zhang, +18

Molecular Cell

Induced Phase SeparationInnate Immune SystemImmunologyTumor ImmunityMutant Nf2 Imprisons +5

Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation

Fansen Meng, Ruyuan Zhou, Shiying Wu, +13

Genes & Development

Transcriptional RegulationSignal TransductionSignaling PathwayCell RegulationViral Immunity +10

IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin

Miao Tian, Xiumei Wang, Jihong Sun, +8

Nature Communications

TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology

Shasha Chen, Shengduo Liu, Jun‐Xian Wang, +14

Molecular Cell

Molecular PhysiologySignal TransductionMitochondrial FunctionMitochondrial DynamicMolecular Biology +4

Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses

Shengduo Liu, Shasha Chen, Xinran Li, +15

Cell Host & Microbe

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseImmunologyAntiviral Response +6

The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration

Ruyuan Zhou, Qirou Wu, Mengqiu Wang, +16

PLoS Biology

Hippo-yap PathwayOrgan RegenerationTranscriptional RegulationSignaling PathwayProtein Expression +19