Molecular Therapy — Nucleic Acids · 2021 · 32 citations · 39 references
Life SciencesBiotechnologyGeneticsGene DeliveryGene TherapyGenome EditingCrispr-cas SystemsEx Vivo Gene DeliveryGene Delivery To Stem CellsIn Vivo Gene DeliveryTherapeutic Genome EditingCrispr-cas9 Ex Vivo EditingCrispr-cas9 Genome EditingGene Knock-inIntracellular Delivery Of Nucleic AcidsMolecular TargetingPrecision Genome Engineering
engineering of cell therapy products.
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau et al. · Science · 2007 · 6.3K citations
Easy quantitative assessment of genome editing by sequence trace decomposition
Eva K. Brinkman, Tao Chen, Mario Amendola et al. · Nucleic Acids Research · 2014 · 2.6K citations · Full text
CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
Cameron J. Turtle, Laïla‐Aïcha Hanafi, Carolina Berger et al. · Journal of Clinical Investigation · 2016 · 2.1K citations · Full text
Medicine, Immunology, Oncology +17