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Publication | Open Access

Generation and Characterization of Torudokimab (LY3375880): A Monoclonal Antibody That Neutralizes Interleukin-33

DOIFull Paper Access

15

Citations

39

References

2021

Year

Angela J. Okragly, Katie Brannon Corwin, Marikka Elia, Dongmei He, Oliver C. Schroeder, Qing Zhang, Tatiyana L. Shiyanova, Stuart W. Bright, Sarah B Dicker, Lukasz K. Chlewicki,
Journal of Inflammation Research

Abstract

Due to torudokimab's high affinity, its ability to completely neutralize IL-33 activity in vitro and in vivo, and the observed cynomolgus monkey pharmacokinetic properties, this molecule was selected for clinical development.

References

YearCitations

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