Concepedia

Publication | Open Access

Inhibition of DNA-PK with AZD7648 Sensitizes Tumor Cells to Radiotherapy and Induces Type I IFN-Dependent Durable Tumor Control

DOIFull Paper Access

52

Citations

57

References

2021

Year

Kyoko Nakamura, Ankur Karmokar, Paul Farrington, Neil H. James, Antonio Ramos‐Montoya, Susan J. Bickerton, Gareth Hughes, Tim Illidge, Elaine Cadogan, Barry R. Davies,
Clinical Cancer Research

Abstract

Blocking the NHEJ DNA repair pathway with AZD7648 in combination with RT leads to durable immune-mediated tumor control.

References

YearCitations

Page 1