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Loss‐of‐Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia

DOIFull Paper Access

114

Citations

32

References

2021

Year

Yi Niu, Ziyou Lin, Arabella Wan, Lei Sun, Shijia Yan, Heng Liang, Siyue Zhan, Dongshi Chen, Xianzhang Bu, Peiqing Liu,
Hepatology

Abstract

Our work identifies ALDOA as an essential driver for HCC cell growth under hypoxia, and we demonstrate that inhibition of ALDOA in the hypoxic TME is a promising therapeutic strategy for treating HCC.

References

YearCitations

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