Concepedia

Identification of potent and selective MTH1 inhibitors

Alessia Petrocchi, Elisabetta Leo, Naphtali J. Reyna, Matthew M. Hamilton, Xi Shi, Connor A. Parker, Faika Mseeh, Jennifer Bardenhagen, Paul G. Leonard, Jason B. Cross,

Bioorganic & Medicinal Chemistry Letters · 2016 · 70 citations · 7 references

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7

Glide:  A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Richard A. Friesner, Jay L. Banks, Robert B. Murphy et al. · Journal of Medicinal Chemistry · 2004 · 9.9K citations

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Extra Precision Glide:  Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand Complexes

Richard A. Friesner, Robert B. Murphy, Matthew P. Repasky et al. · Journal of Medicinal Chemistry · 2006 · 6.9K citations

, , +16

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 529 citations

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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

K. Huber, E. Salah, Branka Radic-Sarikas et al. · Nature · 2014 · 390 citations

, , +11

The Oxidized Deoxynucleoside Triphosphate Pool Is a Significant Contributor to Genetic Instability in Mismatch Repair-Deficient Cells

Maria Teresa Russo, Monica Francesca Blasi, Federica Chiera et al. · Molecular and Cellular Biology · 2003 · 144 citations · Full text

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