Elisabetta Leo

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

Gabriele Zoppoli, Marie Regairaz, Elisabetta Leo et al. · Proceedings of the National Academy of Sciences · 2012 · 375 citations

Medicine, Molecular Biology, Oncology +16

SLFN11 Blocks Stressed Replication Forks Independently of ATR

Junko Murai, Sai-Wen Tang, Elisabetta Leo et al. · Molecular Cell · 2018 · 279 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies

Bhavatarini Vangamudi, Thomas A. Paul, Parantu K. Shah et al. · Cancer Research · 2015 · 270 citations

Life Sciences, Molecular Biology, Oncology +13

Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper

Giuditta Illuzzi, Anna D. Staniszewska, Sonja J. Gill et al. · Clinical Cancer Research · 2022 · 171 citations · Full text

Medicine, Oncology, Pharmacology +13

Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor

Wylie S. Palmer, G. Poncet-Montange, Gang Liu et al. · Journal of Medicinal Chemistry · 2015 · 160 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17