Concepedia

Publication | Open Access

CD8+ T cells inhibit metastasis and CXCL4 regulates its function

DOIFull Paper Access

64

Citations

37

References

2021

Year

Robiya Joseph, Rama Soundararajan, Suhas Vasaikar, Fei Yang, Kendra Allton, Lin Tian, Petra den Hollander, Sevinj Isgandarova, Monika Haemmerle, Barbara Mino,
British Journal of Cancer

Abstract

CD8<sup>+</sup> T cells inhibit metastasis. When the balance between CD8<sup>+</sup> T cells and platelets is disrupted, platelets produce CXCL4, which induces MDSCs thereby inhibiting the CD8<sup>+</sup> T-cell function.

References

YearCitations

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