Concepedia

Acceptor-mediated regioselective enzyme catalyzed sialylation: chemoenzymatic synthesis of GAA-7 ganglioside glycan

Hsin‐Kai Tseng, Yung‐Yu Su, Ting-Wei Chang, Hsin-Chien Liu, Pei‐Jhen Li, Pei‐Yun Chiang, Chun‐Cheng Lin

Chemical Communications · 2021 · 17 citations · 32 references

DOI

Concepts

Abstract

The glycan of GAA-7 was facilely synthesized by enzymatic glycosylation through changing the nonreducing acceptor into GalNH<sub>2</sub> or GalAz to successfully switch the regioselectivity of PmST1.

References

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