Concepedia

Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages

Yinghong Zheng, Jiayuan Kou, Pengyu Wang, Ting Ye, Zitong Wang, Ziyu Gao, Lin Cong, Manman Li, Bowen Dong, Wei Yang,

Aging · 2021 · 53 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

synthesis pathway and, in turn, promoting TFEB nuclear translocation and deacetylation. The functional regulation of SIRT1 and TFEB by berberine could be exploited as a potential therapeutic strategy for atherosclerosis.

References

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