The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity

NIH Image to ImageJ: 25 years of image analysis

Caroline A Schneider, Wayne Rasband, Kevin W. Eliceiri · Nature Methods · 2012 · 65.2K citations

Arts, Computer Science, Visualization +9

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E. Ritchie, Belinda Phipson, Di Wu et al. · Nucleic Acids Research · 2015 · 43K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

Jürgen Cox, Marco Y. Hein, Christian A. Luber et al. · Molecular & Cellular Proteomics · 2014 · 5.5K citations · Full text

Life Sciences, Biochemistry, Protein Biochemistry +16

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Justin Lamb, Emily Crawford, D. D. Peck et al. · Science · 2006 · 5.5K citations

Life Sciences, Bioinformatics, Molecular Biology +16

LocusZoom: regional visualization of genome-wide association scan results

Randall Pruim, Ryan Welch, Serena Sanna et al. · Bioinformatics · 2010 · 3K citations · Full text

Life Sciences, Bioinformatics, Genetics +16