A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis

UCSF Chimera—A visualization system for exploratory research and analysis

Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Journal of Computational Chemistry · 2004 · 47.8K citations

Computing, Bioinformatics, Visualization +17

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

Oleg Trott, Arthur J. Olson · Journal of Computational Chemistry · 2009 · 37.1K citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Clinical implications of high NQO1 expression in breast cancers

Yang� Yang, Yan Zhang, Qunying Wu et al. · Journal of Experimental & Clinical Cancer Research · 2014 · 186 citations · Full text

Medicine, Molecular Biology, Oncology +17

The Crystal Structure of NAD(P)H Quinone Oxidoreductase 1 in Complex with Its Potent Inhibitor Dicoumarol

Gad Asher, Orly Dym, Peter Tsvetkov et al. · Biochemistry · 2006 · 181 citations

Life Sciences, Biochemistry, Molecular Biology +14

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

Xiumei Huang, Edward A. Motea, Zachary Moore et al. · Cancer Cell · 2016 · 132 citations · Full text

Medicine, Oncology, Pharmacology +12