Xiumei Huang

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

Liping Jiang, Ling Xiao, Hidekazu Sugiura et al. · Oncogene · 2014 · 222 citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

Xiumei Huang, Ying Dong, Erik A. Bey et al. · Cancer Research · 2012 · 141 citations · Full text

Medicine, Oncology, Pharmacology +13

Alzheimer's β-Secretase (BACE1) Regulates the cAMP/PKA/CREB Pathway Independently of β-Amyloid

Yaomin Chen, Xiumei Huang, Yun‐wu Zhang et al. · Journal of Neuroscience · 2012 · 140 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

Xiumei Huang, Edward A. Motea, Zachary Moore et al. · Cancer Cell · 2016 · 132 citations · Full text

Medicine, Oncology, Pharmacology +12

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy

Xinpeng Ma, Xiumei Huang, Zachary Moore et al. · Journal of Controlled Release · 2014 · 105 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14