Xiumei Huang

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

Liping Jiang, Ling Xiao, Hidekazu Sugiura et al. · Oncogene · 2014 · 217 citations · Full text

Developmental Biology, Metabolic Reprogramming, Tgfβ1-induced Epithelial-to-mesenchymal Transition +6

Alzheimer's β-Secretase (BACE1) Regulates the cAMP/PKA/CREB Pathway Independently of β-Amyloid

Yaomin Chen, Xiumei Huang, Yun‐wu Zhang et al. · Journal of Neuroscience · 2012 · 139 citations · Full text

Synaptic Transmission, Neurochemical Biomarkers, Amyloid Precursor Protein +25

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

Xiumei Huang, Ying Dong, Erik A. Bey et al. · Cancer Research · 2012 · 138 citations · Full text

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

Xiumei Huang, Edward A. Motea, Zachary Moore et al. · Cancer Cell · 2016 · 127 citations · Full text

Nqo1 Bioactivatable Drug, Tumor Biology, Polymer-drug Conjugate +12

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy

Xinpeng Ma, Xiumei Huang, Zachary Moore et al. · Journal of Controlled Release · 2014 · 105 citations · Full text

Medicinal Chemistry, Drug Targeting, Polymer-drug Conjugate +5