Edward A. Motea

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

Xiumei Huang, Edward A. Motea, Zachary Moore et al. · Cancer Cell · 2016 · 127 citations · Full text

Nqo1 Bioactivatable Drug, Tumor Biology, Polymer-drug Conjugate +12

XRN2 Links Transcription Termination to DNA Damage and Replication Stress

Julio C. Morales, P. Richard, Praveen Patidar et al. · PLoS Genetics · 2016 · 118 citations · Full text

Chromatin, Genome Instability, Transcriptional Regulation +15

Aerosol delivery of stabilized polyester-siRNA nanoparticles to silence gene expression in orthotopic lung tumors

Yunfeng Yan, Ke‐Jin Zhou, Hu Xiong et al. · Biomaterials · 2016 · 66 citations · Full text

Nanoparticles, Nanomedicine, Polyester-sirna Nanoparticles +8

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

Julio C. Morales, P. Richard, Amy Rommel et al. · Nucleic Acids Research · 2014 · 52 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +19

NQO1-dependent, Tumor-selective Radiosensitization of Non–small Cell Lung Cancers

Edward A. Motea, Xiumei Huang, Naveen Singh et al. · Clinical Cancer Research · 2019 · 45 citations