Concepedia

Identification of a new class of HBV capsid assembly modulator

Scott D. Kuduk, Bart Stoops, Richard Alexander, Angela M. Lam, Christine Espiritu, Robert Vogel, Vincent Lau, Klaus Klumpp, Osvaldo Flores, George D. Hartman

Bioorganic & Medicinal Chemistry Letters · 2021 · 16 citations · 13 references

DOI

Concepts

References

13

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

Julie Lucifora, Yuchen Xia, Florian Reisinger et al. · Science · 2014 · 874 citations · Full text

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Inhibition of Hepatitis B Virus Replication by Drug-Induced Depletion of Nucleocapsids

Karl Deres, Claus H. Schröder, Arnold Paessens et al. · Science · 2003 · 506 citations

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Serum hepatitis B virus RNA is encapsidated pregenome RNA that may be associated with persistence of viral infection and rebound

Jie Wang, Tao Shen, Xiangbo Huang et al. · Journal of Hepatology · 2016 · 445 citations · Full text

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Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model

Olaf Weber, K.-H. Schlemmer, Enno Hartmann et al. · Antiviral Research · 2002 · 162 citations

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Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus

Jan Martin Berke, Pascale Dehertogh, Karen Vergauwen et al. · Antimicrobial Agents and Chemotherapy · 2017 · 151 citations · Full text

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