Concepedia

Decitabine and Cisplatin are Synergistic to Exert Anti-Tumor Effect on Gastric Cancer via Inducing Sox2 DNA Demethylation

Zhipeng Zhu, Sihao Lin, Xiaofang Wu, Jiuhua Xu, Lulu Li, Weipeng Ye, Jiayi Li, Zhengjie Huang

OncoTargets and Therapy · 2021 · 15 citations · 29 references

DOIFull text

Open access

Abstract

Cisplatin and decitabine could be synergistic to induce Sox2 DNA demethylation to promote expression of the Sox2 gene, which exerted an anti-tumor effect on GC. It may suggest an insight for innovative therapeutics of GC.

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