Gordon Strathdee

Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter.

Jane A. Plumb, Gordon Strathdee, Julieann Sludden et al. · PubMed · 2000 · 488 citations

Gene Promoter Hypermethylation, High Frequency, Cancer Biology +17

A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

Gordon Strathdee, Melanie Mackean, Maureen Illand et al. · Oncogene · 1999 · 351 citations · Full text

Medicine, Gynecology, Cancer Genomics +9

CpG Island Methylation of DNA Damage Response Genes in Advanced Ovarian Cancer

Jens M. Teodoridis, Jacqueline A. Hall, Sharon Marsh et al. · Cancer Research · 2005 · 254 citations

Phase I and Pharmacodynamic Trial of the DNA Methyltransferase Inhibitor Decitabine and Carboplatin in Solid Tumors

Kim Appleton, Helen Mackay, Ian Judson et al. · Journal of Clinical Oncology · 2007 · 228 citations · Full text

Primary Ovarian Carcinomas Display Multiple Methylator Phenotypes Involving Known Tumor Suppressor Genes

Gordon Strathdee, Kim Appleton, Maureen Illand et al. · American Journal Of Pathology · 2001 · 202 citations

Medicine, Gynecology, Pathology +5