Primary Ovarian Carcinomas Display Multiple Methylator Phenotypes Involving Known Tumor Suppressor Genes

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

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CpG Islands in vertebrate genomes

Margaret Gardiner‐Garden, Marianne Frommer · Journal of Molecular Biology · 1987 · 3.4K citations

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CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota et al. · Proceedings of the National Academy of Sciences · 1999 · 2.5K citations

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Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinoma

James G. Herman, Asad Umar, Kornélia Polyák et al. · Proceedings of the National Academy of Sciences · 1998 · 1.9K citations · Full text

Medicine, Genetics, Oncology +17

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

J Costello, Michael C. Frühwald, Dominic J. Smiraglia et al. · Nature Genetics · 2000 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +14