Michael C. Frühwald

DNA methylation-based classification of central nervous system tumours

David Capper, David Jones, Martin Sill et al. · Nature · 2018 · 2.9K citations · Full text

Neuro-oncology, Dna Methylation-based Classification, Medicine +7

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.6K citations

Chromatin, Neuro-oncology, Chromatin Structure +13

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Dominik Sturm, Hendrik Witt, Volker Hovestadt et al. · Cancer Cell · 2012 · 1.8K citations · Full text

Neuro-oncology, Radiation Oncology, Somatic Variant +11

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

J Costello, Michael C. Frühwald, Dominic J. Smiraglia et al. · Nature Genetics · 2000 · 1.4K citations

Cancer Research, Epigenetic Regulation, Medicine +11

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak et al. · Cell · 2016 · 973 citations · Full text

Neuro-oncology, Molecular Classification, Cerebral Organoid +8