ISG15 protects human Tregs from interferon alpha‐induced contraction in a cell‐intrinsic fashion - Concepedia

Concepedia

Publication | Open Access

ISG15 protects human Tregs from interferon alpha‐induced contraction in a cell‐intrinsic fashion

DOI Full Paper Access

17

Citations

28

References

2020

Year

Ilenia Pacella, Francesca Romana Spinelli, Martina Severa, Eleonora Timperi, Gloria Tucci, Marta Zagaglioni, Fulvia Ceccarelli, Fabiana Rizzo, Eliana M. Coccia, Roosheel S. Patel,

Clinical & Translational Immunology

Abstract

Our results reveal a Treg-intrinsic role of ISG15 in dictating their refractoriness to the IFN signal, thus preserving the Treg population under inflammatory conditions.

References

	Year	Citations

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