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Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer

84

Citations

42

References

2021

Year

Abstract

Our data provide a rationale for clinical evaluation of the therapeutic synergy of the PARPi olaparib and CDK4/6i palbociclib in BRCA<sup>mut</sup>/TNBCs with high Wnt signalling activation and high MYC expression that do not respond to PARPi monotherapy.

References

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