Sensors and Actuators B Chemical · 2020 · 33 citations · 34 references
Life SciencesBiotechnologyMolecular BiologyGenetic EngineeringGenome EditingMolecular BiotechnologyCrispr-based EngineeringCrispr-cas SystemsCas Nuclease SpecificityCrispr-based BiosensorsCrispr-cas12 SystemsIsothermal AmplificationIsothermal Amplification AssaysIsothermal Amplification BiosensorsPolynucleotide Kinase Phosphatase
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CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
Janice S. Chen, Enbo Ma, Lucas B. Harrington et al. · Science · 2018 · 4.4K citations
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
Jonathan S. Gootenberg, Omar O. Abudayyeh, Max J. Kellner et al. · Science · 2018 · 2.6K citations · Full text
CRISPR-Cas12a-assisted nucleic acid detection
Shiyuan Li, Qiuxiang Cheng, Jing-Man Wang et al. · Cell Discovery · 2018 · 1.5K citations · Full text
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
Lucas B. Harrington, David Burstein, Janice S. Chen et al. · Science · 2018 · 1.2K citations · Full text