Concepedia

Probing 4-(diethylamino)-salicylaldehyde-based thiosemicarbazones as multi-target directed ligands against cholinesterases, carbonic anhydrases and α-glycosidase enzymes

Sadaf Hashmi, Samra Khan, Zahid Shafiq, Muhamamd Ishaq, Nastaran Sadeghian, Halide Sedef Karaman, Naeem Akhtar, Muhammad Islam, Asnuzilawati Asari, Habsah Mohamad,

Bioorganic Chemistry · 2020 · 86 citations · 56 references

DOI

Concepts

References

56

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

, , +16

Alzheimer's Disease is Type 3 Diabetes—Evidence Reviewed

Suzanne M. de la Monte, Jack R. Wands · Journal of Diabetes Science and Technology · 2008 · 1.1K citations · Full text

, , +17

Esterase Activities of Human Carbonic Anhydrases B and C

Jacob A. Verpoorte, S. N. Mehta, John T. Edsall · Journal of Biological Chemistry · 1967 · 1K citations · Full text

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A perspective on multi‐target drug discovery and design for complex diseases

Rona R. Ramsay, Marija R. Popović-Nikolić, Katarina Nikolić et al. · Clinical and Translational Medicine · 2018 · 701 citations · Full text

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