Concepedia

Social behaviors and contextual memory of Vcp mutant mice are sensitive to nutrition and can be ameliorated by amino acid supplementation

Tzyy‐Nan Huang, Yu‐Tzu Shih, Si-Cih Lin, Yi‐Ping Hsueh

iScience · 2020 · 14 citations · 38 references

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Concepts

Abstract

-deficient mice, strengthening evidence for the role of protein synthesis in VCP function. Our study illustrates that genetic variation and nutrient factors cross-talk to influence neuronal and behavioral phenotypes.

References

38

De Novo Gene Disruptions in Children on the Autistic Spectrum

Ivan Iossifov, Michael Ronemus, Dan Levy et al. · Neuron · 2012 · 1.5K citations · Full text

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Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

Giles D. Watts, Jill Wymer, Margaret J. Kovach et al. · Nature Genetics · 2004 · 1.4K citations · Full text

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

Yihong Ye, Hemmo Meyer, Tom A. Rapoport · Nature · 2001 · 1.1K citations

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The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

Samantha M. Solon‐Biet, Aisling C. McMahon, J. William O. Ballard et al. · Cell Metabolism · 2014 · 925 citations · Full text

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48

Ernst Jarosch, Christof Taxis, Corinna Volkwein et al. · Nature Cell Biology · 2002 · 536 citations

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